The Serine Protease Inhibitor Elafin Maintains Normal Growth Control by Opposing the Mitogenic Effects of Neutrophil Elastase

The serine protease inhibitor, elafin, is a critical component of the epithelial barrier against neutrophil elastase (NE). Elafin is downregulated in the majority of breast cancer cell lines compared to normal human mammary epithelial cells (HMECs). Here, we evaluated the role of elafin and NE on pr...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncogene
Hlavní autoři: Caruso, Joseph A., Akli, Said, Pageon, Laura, Hunt, Kelly K., Keyomarsi, Khandan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362782/
https://ncbi.nlm.nih.gov/pubmed/25195861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.284
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky