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Protease inhibitors derived from elafin and SLPI and engineered to have enhanced specificity towards neutrophil serine proteases

The secretory leukocyte protease inhibitor (SLPI), elafin, and its biologically active precursor trappin-2 are endogeneous low-molecular weight inhibitors of the chelonianin family that control the enzymatic activity of neutrophil serine proteases (NSPs) like elastase, proteinase 3, and cathepsin G....

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Autori principali: Zani, Marie-Louise, Baranger, Kévin, Guyot, Nicolas, Dallet-Choisy, Sandrine, Moreau, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wiley Subscription Services, Inc., A Wiley Company 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760364/
https://ncbi.nlm.nih.gov/pubmed/19241385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.64
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