A Functional Variant of Elafin With Improved Anti-inflammatory Activity for Pulmonary Inflammation

Elafin is a serine protease inhibitor produced by epithelial and immune cells with anti-inflammatory properties. Research has shown that dysregulated protease activity may elicit proteolytic cleavage of elafin, thereby impairing the innate immune function of the protein. The aim of this study was to...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Small, Donna M, Zani, Marie-Louise, Quinn, Derek J, Dallet-Choisy, Sandrine, Glasgow, Arlene MA, O'Kane, Cecilia, McAuley, Danny F, McNally, Paul, Weldon, Sinéad, Moreau, Thierry, Taggart, Clifford C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426794/
https://ncbi.nlm.nih.gov/pubmed/25189740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.162
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