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Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases

Elafin is a 6 kDa innate immune protein present at several epithelial surfaces including the pulmonary epithelium. It is a canonical protease inhibitor of two neutrophil serine proteases (neutrophil elastase (NE) and proteinase 3) with the capacity to covalently bind extracellular matrix proteins by...

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Detalhes bibliográficos
Main Authors: Guyot, Nicolas, Bergsson, Gudmundur, Butler, Marcus W., Greene, Catherine M., Weldon, Sinead, Kessler, Efrat, Levine, Rodney L., O’Neill, Shane J., Taggart, Clifford C., McElvaney, Noel G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396147/
https://ncbi.nlm.nih.gov/pubmed/20370321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.2010.066
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