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The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity

Secretory Leukocyte Protease Inhibitor (SLPI) is a serine protease inhibitor produced by epithelial and myeloid cells with anti-inflammatory properties. Research has shown that SLPI exerts its anti-inflammatory activity by directly binding to NF-κB DNA binding sites and, in so doing, prevents bindin...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol Res
Hauptverfasser: McGarry, Niamh, Greene, Catherine M., McElvaney, Noel G., Weldon, Sinéad, Taggart, Clifford C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4515294/
https://ncbi.nlm.nih.gov/pubmed/26247039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/507315
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