Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding

Secretory leucoprotease inhibitor (SLPI) is a nonglycosylated protein produced by epithelial cells. In addition to its antiprotease activity, SLPI has been shown to exhibit antiinflammatory properties, including down-regulation of tumor necrosis factor α expression by lipopolysaccharide (LPS) in mac...

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Main Authors: Taggart, Clifford C., Cryan, Sally-Ann, Weldon, Sinead, Gibbons, Aileen, Greene, Catherine M., Kelly, Emer, Low, Teck Boon, O'Neill, Shane J., McElvaney, Noel G.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212970/
https://ncbi.nlm.nih.gov/pubmed/16352738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050768
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