Elafin, an Elastase-specific Inhibitor, Is Cleaved by Its Cognate Enzyme Neutrophil Elastase in Sputum from Individuals with Cystic Fibrosis

Elafin is a neutrophil serine protease inhibitor expressed in lung and displaying anti-inflammatory and anti-bacterial properties. Previous studies demonstrated that some innate host defense molecules of the cystic fibrosis (CF) and chronic obstructive pulmonary disease airways are impaired due to i...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Guyot, Nicolas, Butler, Marcus W., McNally, Paul, Weldon, Sinead, Greene, Catherine M., Levine, Rodney L., O'Neill, Shane J., Taggart, Clifford C., McElvaney, Noel G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2008
Θέματα:
Protein Synthesis, Post-Translational Modification, and Degradation
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583315/
https://ncbi.nlm.nih.gov/pubmed/18799464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803707200
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