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The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase.

Ecotin is a dimeric periplasmic protein from Escherichia coli that has been shown to inhibit potently many trypsin-fold serine proteases of widely varying substrate specificity. To help elucidate the physiological function of ecotin, we examined the family of ecotin orthologues, which are present in...

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Autori principali: Eggers, Christopher T, Murray, Iain A, Delmar, Valerie A, Day, Anthony G, Craik, Charles S
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224055/
https://ncbi.nlm.nih.gov/pubmed/14705961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031790
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