Apoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastase.

The pathogenesis of vasculitis associated with anti-neutrophil cytoplasmic antibodies is not established. The anti-neutrophil cytoplasmic antibody autoanigens proteinase 3 (PR3) and elastase induce detachment and cytolysis of endothelial cells in vitro. We investigated whether PR3 and elastase trigg...

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Hlavní autoři: Yang, J. J., Kettritz, R., Falk, R. J., Jennette, J. C., Gaido, M. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865283/
https://ncbi.nlm.nih.gov/pubmed/8909251
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