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Endothelial tissue factor stimulation by proteinase 3 and elastase

In ANCA-associated vasculitis the activation of primed leucocytes by autoantibodies with subsequent release of proteases such as myeloperoxidase (MPO), proteinase 3 (PR3) and elastase is thought to play an important pathogenetic role. Whether these proteases contribute to the vascular lesions by sti...

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Detalhes bibliográficos
Main Authors: Haubitz, M, Gerlach, M, Kruse, H J, Brunkhorst, R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906245/
https://ncbi.nlm.nih.gov/pubmed/11737080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01587.x
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