טוען...
The BRAF kinase domain promotes the development of gliomas in vivo
In-frame BRAF fusions have been observed in over 80% of sporadic pilocytic astrocytomas. In each fusion, the N-terminal autoinhibitory domain of BRAF is lost, which results in constitutive activation via the retained C-terminal kinase domain (BRAF-KD). We set out to determine if the BRAF-KD is suffi...
שמור ב:
| הוצא לאור ב: | Genes Cancer |
|---|---|
| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Impact Journals LLC
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4362480/ https://ncbi.nlm.nih.gov/pubmed/25821557 |
| תגים: |
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