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Non-peptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity
Lysine demethylases play an important role in epigenetic regulation and thus in the development of diseases like cancer or neurodegenerative disorders. As the lysine specific demethylase 1 (LSD1/KDM1) has been strongly connected to androgen and estrogen dependent gene expression, it serves as a prom...
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| Vydáno v: | J Med Chem |
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| Hlavní autoři: | , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361900/ https://ncbi.nlm.nih.gov/pubmed/24007511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400792m |
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