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Non-peptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity

Lysine demethylases play an important role in epigenetic regulation and thus in the development of diseases like cancer or neurodegenerative disorders. As the lysine specific demethylase 1 (LSD1/KDM1) has been strongly connected to androgen and estrogen dependent gene expression, it serves as a prom...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Med Chem
मुख्य लेखकों: Schmitt, Martin L., Hauser, Alexander-Thomas, Carlino, Luca, Pippel, Martin, Schulz-Fincke, Johannes, Metzger, Eric, Willmann, Dominica, Yiu, Teresa, Barton, Michelle, Schüle, Roland, Sippl, Wolfgang, Jung, Manfred
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361900/
https://ncbi.nlm.nih.gov/pubmed/24007511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400792m
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