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Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer

Studies of alterations in histone methylation in cancer have led to the identification of histone methyltransferases and demethylases as novel targets for therapy. Lysine-specific demethylase 1 (LSD1, also known as KDM1A), demethylates H3K4me1/2, or H3K9me1/2 in a context-dependent manner. In additi...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Majello, Barbara, Gorini, Francesca, Saccà, Carmen Daniela, Amente, Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6468368/
https://ncbi.nlm.nih.gov/pubmed/30866496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030324
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