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Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer
Studies of alterations in histone methylation in cancer have led to the identification of histone methyltransferases and demethylases as novel targets for therapy. Lysine-specific demethylase 1 (LSD1, also known as KDM1A), demethylates H3K4me1/2, or H3K9me1/2 in a context-dependent manner. In additi...
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| Veröffentlicht in: | Cancers (Basel) |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6468368/ https://ncbi.nlm.nih.gov/pubmed/30866496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030324 |
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