A carregar...

Non-peptidic propargylamines as inhibitors of lysine specific demethylase 1 (LSD1) with cellular activity

Lysine demethylases play an important role in epigenetic regulation and thus in the development of diseases like cancer or neurodegenerative disorders. As the lysine specific demethylase 1 (LSD1/KDM1) has been strongly connected to androgen and estrogen dependent gene expression, it serves as a prom...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Schmitt, Martin L., Hauser, Alexander-Thomas, Carlino, Luca, Pippel, Martin, Schulz-Fincke, Johannes, Metzger, Eric, Willmann, Dominica, Yiu, Teresa, Barton, Michelle, Schüle, Roland, Sippl, Wolfgang, Jung, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361900/
https://ncbi.nlm.nih.gov/pubmed/24007511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm400792m
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!