Novel Pharmacological Treatment Attenuates Septic Shock and Improves Long-Term Survival

BACKGROUND: We have previously demonstrated that suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, improves survival in a lipopolysaccharide (LPS)-induced lethal endotoxemia model. The goal of this study was to investigate the impact of SAHA on survival in a more clinically re...

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Detalhes bibliográficos
Publicado no:Surgery
Main Authors: Zhao, Ting, Li, Yongqing, Liu, Baoling, Liu, Zhengcai, Chong, Wei, Duan, Xiuzhen, Deperalta, Danielle K., Velmahos, George C., Alam, Hasan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361041/
https://ncbi.nlm.nih.gov/pubmed/23889949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2013.04.003
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