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Effects of hyperglycemia on lonidamine-induced acidification and de-energization of human melanoma xenografts and sensitization to melphalan
We seek to exploit the natural tendency of melanomas and other tumors to convert glucose to lactate as a method for selective intracellular acidification of cancer cells and for potentiating the activity of N-mustard antineoplastic agents. We performed this study to evaluate whether induction of hyp...
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| 出版年: | NMR Biomed |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4361035/ https://ncbi.nlm.nih.gov/pubmed/25702942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.3260 |
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