Comparison of the Lonidamine Potentiated Effect of Nitrogen Mustard Alkylating Agents on the Systemic Treatment of DB-1 Human Melanoma Xenografts in Mice

Previous NMR studies demonstrated that lonidamine (LND) selectively diminishes the intracellular pH (pHi) of DB-1 melanoma and mouse xenografts of a variety of other prevalent human cancers while decreasing their bioenergetic status (tumor βNTP/Pi ratio) and enhancing the activities of melphalan and...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nath, Kavindra, Nelson, David S., Putt, Mary E., Leeper, Dennis B., Garman, Bradley, Nathanson, Katherine L., Glickson, Jerry D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902256/
https://ncbi.nlm.nih.gov/pubmed/27285585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157125
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