Effect of Differences in Metabolic Activity of Melanoma Models on Response to Lonidamine plus Doxorubicin

Lonidamine (LND), a metabolic modulator, sensitizes DB-1 human melanoma to doxorubicin (DOX) chemotherapy by acidifying and de-energizing the tumor. This report compares the effects of LND on two human melanoma lines, DB-1 and WM983B, which exhibit different metabolic properties. Using liquid chroma...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Nath, Kavindra, Roman, Jeffrey, Nelson, David S., Guo, Lili, Lee, Seung-Cheol, Orlovskiy, Stepan, Muriuki, Kevin, Heitjan, Daniel F., Pickup, Stephen, Leeper, Dennis B., Blair, Ian A., Putt, Mary E., Glickson, Jerry D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6168452/
https://ncbi.nlm.nih.gov/pubmed/30279592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33019-4
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