Mechanism of Antineoplastic Activity of Lonidamine

Lonidamine (LND) was initially introduced as an antispermatogenic agent. It was later found to have anticancer activity sensitizing tumors to chemo-, radio-, photodynamic-therapy and hyperthermia. Although the mechanism of action remained unclear, LND treatment has been known to target metabolic pat...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Nath, Kavindra, Guo, Lili, Nancolas, Bethany, Nelson, David S., Shestov, Alexander A, Lee, Seung-Cheol, Roman, Jeffrey, Zhou, Rong, Leeper, Dennis B., Halestrap, Andrew P., Blair, Ian A., Glickson, Jerry D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5138080/
https://ncbi.nlm.nih.gov/pubmed/27497601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2016.08.001
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