Optical Redox Imaging of Lonidamine Treatment Response of Melanoma Cells and Xenografts

PURPOSE: Fluorescence of co-enzyme reduced nicotinamide adenine dinucleotide (NADH) and oxidized flavoproteins (Fp) provides a sensitive measure of the mitochondrial redox state and cellular metabolism. By imaging NADH and Fp, we investigated the utility of optical redox imaging (ORI) to monitor cel...

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Bibliografske podrobnosti
izdano v:Mol Imaging Biol
Main Authors: Xu, He N., Feng, Min, Nath, Kavindra, Nelson, David, Roman, Jeff, Zhao, Huaqing, Lin, Zhenwu, Glickson, Jerry, Li, Lin Z.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525077/
https://ncbi.nlm.nih.gov/pubmed/30151646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-018-1258-z
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