Second-generation Notch1 activity-trap mouse line (N1IP::Cre(HI)) provides a more comprehensive map of cells experiencing Notch1 activity

We have previously described the creation and analysis of a Notch1 activity-trap mouse line, Notch1 intramembrane proteolysis-Cre6MT or N1IP::Cre(LO), that marked cells experiencing relatively high levels of Notch1 activation. Here, we report and characterize a second line with improved sensitivity...

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Gepubliceerd in:Development
Hoofdauteurs: Liu, Zhenyi, Brunskill, Eric, Boyle, Scott, Chen, Shuang, Turkoz, Mustafa, Guo, Yuxuan, Grant, Rachel, Kopan, Raphael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360173/
https://ncbi.nlm.nih.gov/pubmed/25725069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.119529
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