In Vivo Visualization of Notch1 Proteolysis Reveals the Heterogeneity of Notch1 Signaling Activity in the Mouse Cochlea

Mechanosensory hair cells (HCs) and surrounding supporting cells (SCs) in the mouse cochlea are important for hearing and are derived from the same prosensory progenitors. Notch1 signaling plays dual but contrasting and age-dependent roles in mouse cochlear development: early lateral induction and s...

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Bibliographic Details
Main Authors: Liu, Zhiyong, Liu, Zhenyi, Walters, Bradley J., Owen, Thomas, Kopan, Raphael, Zuo, Jian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669271/
https://ncbi.nlm.nih.gov/pubmed/23741415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064903
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