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In Vivo Visualization of Notch1 Proteolysis Reveals the Heterogeneity of Notch1 Signaling Activity in the Mouse Cochlea

Mechanosensory hair cells (HCs) and surrounding supporting cells (SCs) in the mouse cochlea are important for hearing and are derived from the same prosensory progenitors. Notch1 signaling plays dual but contrasting and age-dependent roles in mouse cochlear development: early lateral induction and s...

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Detalhes bibliográficos
Main Authors: Liu, Zhiyong, Liu, Zhenyi, Walters, Bradley J., Owen, Thomas, Kopan, Raphael, Zuo, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669271/
https://ncbi.nlm.nih.gov/pubmed/23741415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064903
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