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Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE

The four highly conserved Notch (N) receptors receive short-range signals that control many biological processes during development and in adult vertebrate tissues. The involvement of Notch1 signaling in tissue self-renewal is less clear, however. We developed a novel genetic approach N(1)IP-CRE (No...

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Main Authors: Vooijs, Marc, Ong, Chintong, Hadland, Brandon, Huppert, Stacey, Liu, Zhenyi, Korving, Jeroen, van den Born, Maaike, Stappenbeck, Thaddeus, Wu, Yumei, Clevers, Hans, Kopan, Raphael
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583343/
https://ncbi.nlm.nih.gov/pubmed/17215306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02733
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