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Alagille, Notch, and robustness: why duplicating systems does not produce redundancy

The mammalian kidney forms from several populations of progenitors that only persist during embryogenesis. The epithelial nephron progenitors reside in the cap mesenchyme (CM), whereas mesangial and endothelial cell progenitors reside in the neighboring stromal mesenchyme (SM). After a ureteric bud...

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Autores principales: Kopan, Raphael, Chen, Shuang, Liu, Zhenyi
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951435/
https://ncbi.nlm.nih.gov/pubmed/24271660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2661-y
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