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Alagille, Notch, and robustness: why duplicating systems does not produce redundancy

The mammalian kidney forms from several populations of progenitors that only persist during embryogenesis. The epithelial nephron progenitors reside in the cap mesenchyme (CM), whereas mesangial and endothelial cell progenitors reside in the neighboring stromal mesenchyme (SM). After a ureteric bud...

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Detalhes bibliográficos
Main Authors: Kopan, Raphael, Chen, Shuang, Liu, Zhenyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951435/
https://ncbi.nlm.nih.gov/pubmed/24271660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2661-y
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