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Alagille, Notch, and robustness: why duplicating systems does not produce redundancy

The mammalian kidney forms from several populations of progenitors that only persist during embryogenesis. The epithelial nephron progenitors reside in the cap mesenchyme (CM), whereas mesangial and endothelial cell progenitors reside in the neighboring stromal mesenchyme (SM). After a ureteric bud...

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Main Authors: Kopan, Raphael, Chen, Shuang, Liu, Zhenyi
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951435/
https://ncbi.nlm.nih.gov/pubmed/24271660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-013-2661-y
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