P2X7 receptor inhibition protects against ischemic acute kidney injury in mice

Activation of the purinergic P2X7 receptor (P2X7R) has been associated with the development of experimental nephritis and diabetic and hypertensive nephropathy. However, its role in acute kidney injury (AKI) remains unknown. In this study, we examined the effects of P2X7R inhibition in a murine mode...

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Pubblicato in:Am J Physiol Cell Physiol
Autori principali: Yan, Yanli, Bai, Jianwen, Zhou, Xiaoxu, Tang, Jinhua, Jiang, Chunming, Tolbert, Evelyn, Bayliss, George, Gong, Rujun, Zhao, Ting C., Zhuang, Shougang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360025/
https://ncbi.nlm.nih.gov/pubmed/25588875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00245.2014
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