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P2X7 receptor inhibition protects against ischemic acute kidney injury in mice

Activation of the purinergic P2X7 receptor (P2X7R) has been associated with the development of experimental nephritis and diabetic and hypertensive nephropathy. However, its role in acute kidney injury (AKI) remains unknown. In this study, we examined the effects of P2X7R inhibition in a murine mode...

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Bibliografski detalji
Izdano u:Am J Physiol Cell Physiol
Glavni autori: Yan, Yanli, Bai, Jianwen, Zhou, Xiaoxu, Tang, Jinhua, Jiang, Chunming, Tolbert, Evelyn, Bayliss, George, Gong, Rujun, Zhao, Ting C., Zhuang, Shougang
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360025/
https://ncbi.nlm.nih.gov/pubmed/25588875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00245.2014
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