P2X7 receptor inhibition protects against ischemic acute kidney injury in mice

Activation of the purinergic P2X7 receptor (P2X7R) has been associated with the development of experimental nephritis and diabetic and hypertensive nephropathy. However, its role in acute kidney injury (AKI) remains unknown. In this study, we examined the effects of P2X7R inhibition in a murine mode...

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Gepubliceerd in:Am J Physiol Cell Physiol
Hoofdauteurs: Yan, Yanli, Bai, Jianwen, Zhou, Xiaoxu, Tang, Jinhua, Jiang, Chunming, Tolbert, Evelyn, Bayliss, George, Gong, Rujun, Zhao, Ting C., Zhuang, Shougang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360025/
https://ncbi.nlm.nih.gov/pubmed/25588875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00245.2014
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