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Lis1 regulates dynein by sterically blocking its mechanochemical cycle
Regulation of cytoplasmic dynein's motor activity is essential for diverse eukaryotic functions, including cell division, intracellular transport, and brain development. The dynein regulator Lis1 is known to keep dynein bound to microtubules; however, how this is accomplished mechanistically re...
में बचाया:
| में प्रकाशित: | eLife |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
eLife Sciences Publications, Ltd
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359366/ https://ncbi.nlm.nih.gov/pubmed/25380312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03372 |
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