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Lis1 is an initiation factor for dynein-driven organelle transport

The molecular motor cytoplasmic dynein is responsible for most minus-end–directed, microtubule-based transport in eukaryotic cells. It is especially important in neurons, where defects in microtubule-based motility have been linked to neurological diseases. For example, lissencephaly is caused by mu...

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Hlavní autoři: Egan, Martin J., Tan, Kaeling, Reck-Peterson, Samara L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384415/
https://ncbi.nlm.nih.gov/pubmed/22711696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201112101
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