SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination

Aberrant elevation of JARID1B and histone H3 lysine 4 trimethylation (H3K4me3) is frequently observed in many diseases including prostate cancer (PCa), yet the mechanisms on the regulation of JARID1B and H3K4me3 through epigenetic alterations still remain poorly understood. Here we report that Skp2...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Lu, Wenfu, Liu, Shenji, Li, Bo, Xie, Yingqiu, Adhiambo, Christine, Yang, Qing, Ballard, Billy R., Nakayama, Keiichi I., Matusik, Robert J., Chen, Zhenbang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2014
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359254/
https://ncbi.nlm.nih.gov/pubmed/25596733
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