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Skp2 Regulates Receptor Through Ubiquitin-Mediated Degradation Independent of Akt/mTOR Pathways in Prostate Cancer

BACKGROUND: The intervention of advanced prostate cancer (PCa) in patients has been commonly depending on androgen deprivation therapy. Despite of tremendous research efforts, however, molecular mechanisms on AR regulation remain poorly understood, particularly for castration resistant prostate canc...

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Detalhes bibliográficos
Main Authors: Li, Bo, Lu, Wenfu, Yang, Qing, Yu, Xiuping, Matusik, Robert J., Chen, Zhenbang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062570/
https://ncbi.nlm.nih.gov/pubmed/24347472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22763
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