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2-MeS-β,γ-CCl(2)-ATP is a Potent Agent for Reducing Intraocular Pressure()

Extracellular nucleotides can modify the production or drainage of the aqueous humor via activation of P2 receptors and therefore affect the intraocular pressure (IOP). We have synthesized slowly hydrolyzable nucleoside di- and triphosphate analogues, 1, and 8–14. Analogues 8–14 were completely resi...

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Bibliografske podrobnosti
izdano v:J Med Chem
Main Authors: Eliahu, Shay, Martín-Gil, Alba, de Lara, María Jesús Perez, Pintor, Jesús, Camden, Jean, Weisman, Gary A., Lecka, Joanna, Sévigny, Jean, Fischer, Bilha
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358770/
https://ncbi.nlm.nih.gov/pubmed/20337495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100030u
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