2-MeS-β,γ-CCl(2)-ATP is a Potent Agent for Reducing Intraocular Pressure()

Extracellular nucleotides can modify the production or drainage of the aqueous humor via activation of P2 receptors and therefore affect the intraocular pressure (IOP). We have synthesized slowly hydrolyzable nucleoside di- and triphosphate analogues, 1, and 8–14. Analogues 8–14 were completely resi...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Eliahu, Shay, Martín-Gil, Alba, de Lara, María Jesús Perez, Pintor, Jesús, Camden, Jean, Weisman, Gary A., Lecka, Joanna, Sévigny, Jean, Fischer, Bilha
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358770/
https://ncbi.nlm.nih.gov/pubmed/20337495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100030u
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