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Identification of hydrolytically stable and selective P2Y(1) receptor agonists
P2Y nucleotide receptors (P2YRs) are attractive pharmaceutical targets. Most P2YR agonists proposed as drugs consist of a nucleotide scaffold, but their use is limited due to their chemical and enzymatic instabilities. To identify drug candidates, we developed non-hydrolyzable P2YR agonists. We synt...
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| Udgivet i: | Eur J Med Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354951/ https://ncbi.nlm.nih.gov/pubmed/18760862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2008.07.015 |
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