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A Novel Insulin Secretagogue Based on a Dinucleoside Polyphosphate Scaffold

Dinucleoside polyphosphates exert their physiological effects via P2 receptors (P2Rs). They are attractive drug candidates, as they offer better stability and specificity compared to nucleotides, the most common P2 receptor ligands. The activation of pancreatic P2Y receptors by nucleotides increases...

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Dades bibliogràfiques
Publicat a:J Med Chem
Autors principals: Eliahu, Shay, Barr, Haim M., Camden, Jean, Weisman, Gary A., Fischer, Bilha
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363086/
https://ncbi.nlm.nih.gov/pubmed/20175517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901621h
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