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A Novel Insulin Secretagogue Based on a Dinucleoside Polyphosphate Scaffold
Dinucleoside polyphosphates exert their physiological effects via P2 receptors (P2Rs). They are attractive drug candidates, as they offer better stability and specificity compared to nucleotides, the most common P2 receptor ligands. The activation of pancreatic P2Y receptors by nucleotides increases...
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| Veröffentlicht in: | J Med Chem |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363086/ https://ncbi.nlm.nih.gov/pubmed/20175517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901621h |
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