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Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth
INTRODUCTION: Human epidermal growth factor receptor HER3 has been implicated in promoting the aggressiveness and metastatic potential of breast cancer. Upregulation of HER3 has been found to be a major mechanism underlying drug resistance to EGFR and HER2 tyrosine kinase inhibitors and to endocrine...
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| Publicado no: | Breast Cancer Res |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358700/ https://ncbi.nlm.nih.gov/pubmed/25849870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-015-0528-9 |
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