Rictor/mTORC2 Pathway in Oocytes Regulates Folliculogenesis, and Its Inactivation Causes Premature Ovarian Failure

Molecular basis of ovarian folliculogenesis and etiopathogenesis of premature ovarian failure (POF), a common cause of infertility in women, are not fully understood. Mechanistic target of rapamycin complex 2 (mTORC2) is emerging as a central regulator of cell metabolism, proliferation, and survival...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Chen, Zhenguo, Kang, Xiangjin, Wang, Liping, Dong, Heling, Wang, Caixia, Xiong, Zhi, Zhao, Wanlu, Jia, Chunhong, Lin, Jun, Zhang, Wen, Yuan, Weiping, Zhong, Mei, Du, Hongzi, Bai, Xiaochun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358274/
https://ncbi.nlm.nih.gov/pubmed/25564616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605261
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