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Oncoprotein YAP Regulates the Spindle Checkpoint Activation in a Mitotic Phosphorylation-dependent Manner through Up-regulation of BubR1

The transcriptional co-activator YAP (Yes-associated protein) functions as an oncogene; however, it is largely unclear how YAP exerts its oncogenic role. In this study, we further explored the functional significance of YAP and its mitotic phosphorylation in the spindle checkpoint. We found that the...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Yang, Shuping, Zhang, Lin, Chen, Xingcheng, Chen, Yuanhong, Dong, Jixin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358258/
https://ncbi.nlm.nih.gov/pubmed/25605730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624411
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