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Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

Autophagy is an intracellular degradation pathway and is considered to be an essential cell survival mechanism. Defects in autophagy are implicated in many pathological processes, including inflammatory bowel disease. Among the innate defense mechanisms of intestinal mucosa, a defective tight juncti...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Nighot, Prashant K., Hu, Chien-An Andy, Ma, Thomas Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358142/
https://ncbi.nlm.nih.gov/pubmed/25616664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597492
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