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Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

Autophagy is an intracellular degradation pathway and is considered to be an essential cell survival mechanism. Defects in autophagy are implicated in many pathological processes, including inflammatory bowel disease. Among the innate defense mechanisms of intestinal mucosa, a defective tight juncti...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Nighot, Prashant K., Hu, Chien-An Andy, Ma, Thomas Y.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358142/
https://ncbi.nlm.nih.gov/pubmed/25616664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597492
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