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Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

Autophagy is an intracellular degradation pathway and is considered to be an essential cell survival mechanism. Defects in autophagy are implicated in many pathological processes, including inflammatory bowel disease. Among the innate defense mechanisms of intestinal mucosa, a defective tight juncti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nighot, Prashant K., Hu, Chien-An Andy, Ma, Thomas Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358142/
https://ncbi.nlm.nih.gov/pubmed/25616664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.597492
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