טוען...
Regulation of Sarcoplasmic Reticulum Ca(2+) ATPase 2 (SERCA2) Activity by Phosphodiesterase 3A (PDE3A) in Human Myocardium: PHOSPHORYLATION-DEPENDENT INTERACTION OF PDE3A1 WITH SERCA2
Cyclic nucleotide phosphodiesterase 3A (PDE3) regulates cAMP-mediated signaling in the heart, and PDE3 inhibitors augment contractility in patients with heart failure. Studies in mice showed that PDE3A, not PDE3B, is the subfamily responsible for these inotropic effects and that murine PDE3A1 associ...
שמור ב:
| הוצא לאור ב: | J Biol Chem |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4358103/ https://ncbi.nlm.nih.gov/pubmed/25593322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.638585 |
| תגים: |
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