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GIV/Girdin Transmits Signals from Multiple Receptors by Triggering Trimeric G Protein Activation

Activation of trimeric G proteins has been traditionally viewed as the exclusive job of G protein-coupled receptors (GPCRs). This view has been challenged by the discovery of non-receptor activators of trimeric G proteins. Among them, GIV (a.k.a. Girdin) is the first for which a guanine nucleotide e...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Garcia-Marcos, Mikel, Ghosh, Pradipta, Farquhar, Marilyn G.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4358093/
https://ncbi.nlm.nih.gov/pubmed/25605737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.613414
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