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Activation of Gαi3 triggers cell migration via regulation of GIV
During migration, cells must couple direction sensing to signal transduction and actin remodeling. We previously identified GIV/Girdin as a Gαi3 binding partner. We demonstrate that in mammalian cells Gαi3 controls the functions of GIV during cell migration. We find that Gαi3 preferentially localize...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483528/ https://ncbi.nlm.nih.gov/pubmed/18663145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200712066 |
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