GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression

GIV/Girdin is a multidomain signaling molecule that enhances PI3K-Akt signals downstream of both G protein-coupled and growth factor receptors. We previously reported that GIV triggers cell migration via its C-terminal guanine nucleotide exchange factor (GEF) motif that activates Gαi. Recently we di...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ghosh, Pradipta, Garcia-Marcos, Mikel, Farquhar, Marilyn G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
Konular:
Commentary & View
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210208/
https://ncbi.nlm.nih.gov/pubmed/21546796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.3.15909
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller