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GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression
GIV/Girdin is a multidomain signaling molecule that enhances PI3K-Akt signals downstream of both G protein-coupled and growth factor receptors. We previously reported that GIV triggers cell migration via its C-terminal guanine nucleotide exchange factor (GEF) motif that activates Gαi. Recently we di...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Landes Bioscience
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210208/ https://ncbi.nlm.nih.gov/pubmed/21546796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.3.15909 |
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