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GIV/Girdin Links Vascular Endothelial Growth Factor Signaling to Akt Survival Signaling in Podocytes Independent of Nephrin

Podocytes are critically involved in the maintenance of the glomerular filtration barrier and are key targets of injury in many glomerular diseases. Chronic injury leads to progressive loss of podocytes, glomerulosclerosis, and renal failure. Thus, it is essential to maintain podocyte survival and a...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Wang, Honghui, Misaki, Taro, Taupin, Vanessa, Eguchi, Akiko, Ghosh, Pradipta, Farquhar, Marilyn G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310647/
https://ncbi.nlm.nih.gov/pubmed/25012178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013090985
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