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A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

Autophagy is the major catabolic process responsible for the removal of aggregated proteins and damaged organelles. Autophagy is regulated by both G proteins and growth factors, but the underlying mechanism of how they are coordinated during initiation and reversal of autophagy is unknown. Using pro...

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Detalhes bibliográficos
Main Authors: Garcia-Marcos, Mikel, Ear, Jason, Farquhar, Marilyn G., Ghosh, Pradipta
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046063/
https://ncbi.nlm.nih.gov/pubmed/21209316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-08-0738
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