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Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging
The ability of DNA glycosylases to rapidly and efficiently detect lesions among a vast excess of nondamaged DNA bases is vitally important in base excision repair (BER). Here, we use single molecule imaging by atomic force microscopy (AFM) supported by a 2-aminopurine fluorescence base flipping assa...
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| Publicado en: | Nucleic Acids Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4357730/ https://ncbi.nlm.nih.gov/pubmed/25712093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv139 |
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