טוען...
Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition
Cytosine methylation at CpG dinucleotides produces m(5)CpG, an epigenetic modification that is important for transcriptional regulation and genomic stability in vertebrate cells. However, m(5)C deamination yields mutagenic G·T mispairs, which are implicated in genetic disease, cancer, and aging. Hum...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
National Academy of Sciences
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2449336/ https://ncbi.nlm.nih.gov/pubmed/18587051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711061105 |
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