Načítá se...
Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition
Cytosine methylation at CpG dinucleotides produces m(5)CpG, an epigenetic modification that is important for transcriptional regulation and genomic stability in vertebrate cells. However, m(5)C deamination yields mutagenic G·T mispairs, which are implicated in genetic disease, cancer, and aging. Hum...
Uloženo v:
| Hlavní autoři: | , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2449336/ https://ncbi.nlm.nih.gov/pubmed/18587051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711061105 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|